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SB 216641 hydrochloride
CAS No. 193611-67-5
SB 216641 hydrochloride( —— )
Catalog No. M33924 CAS No. 193611-67-5
SB 216641 hydrochloride (SB-216641A) is a selective 5-HT1B/D receptor antagonist with anxiolytic properties that antagonizes the vasoconstrictor response mediated by sumatriptan.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 103 | Get Quote |
|
| 5MG | 160 | Get Quote |
|
| 10MG | 237 | Get Quote |
|
| 25MG | 385 | Get Quote |
|
| 50MG | 563 | Get Quote |
|
| 100MG | 780 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSB 216641 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionSB 216641 hydrochloride (SB-216641A) is a selective 5-HT1B/D receptor antagonist with anxiolytic properties that antagonizes the vasoconstrictor response mediated by sumatriptan.
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DescriptionSB-216641A (SB-216641 hydrochloride) is a selective antagonist of 5-HT1B/D receptor. SB-216641A shows high affinity and selectivity for h5-HT1B receptors over h5-HT1D receptors. SB-216641A inhibits the function of SKF-99101H.
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In Vitro——
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In VivoAnimal Model:Guinea pigs.Dosage:0.6, 2.0, 6.0 and 20.0 mg/kg.Administration:Intraperitoneal injection; single dose.Result:Significantly blocked the effects of SKF-99101H.Animal Model:Dogs.Dosage:559 nmol/kg. Administration:Intravenous injection; single dose.Result:Improved the gastric relaxation.
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Synonyms——
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number193611-67-5
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Formula Weight523.02
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Molecular FormulaC28H31ClN4O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.O=C(NC1=CC=C(OC)C(OCCN(C)C)=C1)C=2C=CC(=CC2)C=3C=CC(=CC3C)C4=NOC(=N4)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hagan JJ, et al. Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig. Eur J Pharmacol. 1997 Jul 23;331(2-3):169-74. ?
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